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Thiazole formation through a modified Gewald reaction

The synthesis of thiazoles and thiophenes starting from nitriles, via a modified Gewald reaction has been studied for a number of different substrates. 1,4-Dithiane-2,5-diol was used as the aldehyde precursor to give either 2-substituted thiazoles or 2-substituted aminothiophenes depending on the su...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Mallia, Carl J, Englert, Lukas, Walter, Gary C, Baxendale, Ian R
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4464301/
https://ncbi.nlm.nih.gov/pubmed/26124889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.11.98
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