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Cyanoacetamide MCR (III): Three-Component Gewald Reactions Revisited
Cyanoacetic acid derivatives are the starting materials for a plethora of multicomponent reaction (MCR) scaffolds. Here we describe valuable general protocols for the synthesis of arrays of 2-aminothiophene-3-carboxamides from cyanoacetamides, aldehydes or ketones and sulfur via a Gewald-3CR variati...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3721980/ https://ncbi.nlm.nih.gov/pubmed/19958011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cc9001586 |
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