Development of Glucose Regulated Protein 94-Selective Inhibitors Based on the BnIm and Radamide Scaffold

Glucose regulated protein 94 (Grp94) is the endoplasmic reticulum resident of the heat shock protein 90 kDa (Hsp90) family of molecular chaperones. Grp94 associates with many proteins involved in cell adhesion and signaling, including integrins, Toll-like receptors, immunoglobulins, and mutant myoci...

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Detaylı Bibliyografya
Yayımlandı:J Med Chem
Asıl Yazarlar: Crowley, Vincent M., Khandelwal, Anuj, Mishra, Sanket, Stothert, Andrew R., Huard, Dustin J. E., Zhao, Jinbo, Muth, Aaron, Duerfeldt, Adam S., Kizziah, James L., Lieberman, Raquel L., Dickey, Chad A., Blagg, Brian S. J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2016
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979570/
https://ncbi.nlm.nih.gov/pubmed/27003516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.6b00085
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