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Common and Unique Genetic Interactions of the Poly(ADP-ribose) Polymerases PARP1 and PARP2 with DNA Double-Strand Break Repair Pathways
In mammalian cells, chromatin poly(ADP-ribos)ylation (PARylation) at sites of DNA Double-Strand Breaks (DSBs) is mediated by two highly related enzymes, PARP1 and PARP2. However, enzyme-specific genetic interactions with other DSB repair factors remain largely undefined. In this context, it was prev...
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| Опубликовано в: : | DNA Repair (Amst) |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2016
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979568/ https://ncbi.nlm.nih.gov/pubmed/27373144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.06.001 |
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