Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery

BACKGROUND: The cytotoxicity and the rejoining of DNA double-strand breaks induced by γ-rays, H(2)O(2 )and neocarzinostatin, were investigated in normal and PARP-1 knockout mouse 3T3 fibroblasts to determine the role of poly(ADP-ribose) polymerase (PARP-1) in DNA double-strand break repair. RESULTS:...

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Detalhes bibliográficos

Publicado no:	BMC Cell Biol
Principais autores:	Noël, Georges, Giocanti, Nicole, Fernet, Marie, Mégnin-Chanet, Frédérique, Favaudon, Vincent
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2003
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC179890/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12866953/ https://ncbi.nlm.nih.govhttps://doi.org/10.1186/1471-2121-4-7
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