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Poly(ADP-ribose) polymerase (PARP-1) is not involved in DNA double-strand break recovery
BACKGROUND: The cytotoxicity and the rejoining of DNA double-strand breaks induced by γ-rays, H(2)O(2 )and neocarzinostatin, were investigated in normal and PARP-1 knockout mouse 3T3 fibroblasts to determine the role of poly(ADP-ribose) polymerase (PARP-1) in DNA double-strand break repair. RESULTS:...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC179890/ https://ncbi.nlm.nih.gov/pubmed/12866953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2121-4-7 |
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