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Common and Unique Genetic Interactions of the Poly(ADP-ribose) Polymerases PARP1 and PARP2 with DNA Double-Strand Break Repair Pathways
In mammalian cells, chromatin poly(ADP-ribos)ylation (PARylation) at sites of DNA Double-Strand Breaks (DSBs) is mediated by two highly related enzymes, PARP1 and PARP2. However, enzyme-specific genetic interactions with other DSB repair factors remain largely undefined. In this context, it was prev...
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| 出版年: | DNA Repair (Amst) |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4979568/ https://ncbi.nlm.nih.gov/pubmed/27373144 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2016.06.001 |
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