SAG-UPS attenuates proapoptotic SARM and Noxa to confer survival advantage to early hepatocellular carcinoma

Hepatocellular carcinoma (HCC) is a deadly cancer because of its commonly late diagnosis and limited treatment options. SAG (sensitive to apoptosis gene)-dependent UPS (ubiquitin–proteasome system) is a key switch between immune-mediated apoptosis and overactivation-mediated protumorigenesis, prompt...

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Udgivet i:Cell Death Discov
Main Authors: Chang, S C, Choo, W Q W, Toh, H C, Ding, J L
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979479/
https://ncbi.nlm.nih.gov/pubmed/27551463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddiscovery.2015.32
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