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Loss of T‐bet confers survival advantage to influenza–bacterial superinfection

The transcription factor, T‐bet, regulates type 1 inflammatory responses against a range of infections. Here, we demonstrate a previously unaddressed role of T‐bet, to influenza virus and bacterial superinfection. Interestingly, we found that T‐bet deficiency did not adversely affect the efficacy of...

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Bibliografiske detaljer
Udgivet i:EMBO J
Main Authors: Er, Jun Zhi, Koean, Ricky Abdi Gunawan, Ding, Jeak Ling
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6315292/
https://ncbi.nlm.nih.gov/pubmed/30322895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201899176
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