Proapoptotic Noxa is required for particulate matter-induced cell death and lung inflammation

Elevated ambient levels of particulate matter air pollution are associated with excess daily mortality, largely attributable to increased rates of cardiovascular events. We have previously reported that particulate matter induces p53-dependent apoptosis in primary human alveolar epithelial cells. Ac...

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Autori principali: Urich, Daniela, Soberanes, Saul, Burgess, Zach, Chiarella, Sergio E., Ghio, Andrew J., Ridge, Karen M., Kamp, David W., Chandel, Navdeep S., Mutlu, Gökhan M., Budinger, G. R. Scott
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Federation of American Societies for Experimental Biology 2009
Soggetti:
Research Communications
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704586/
https://ncbi.nlm.nih.gov/pubmed/19237507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.08-114546
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