Particulate Matter-Induced Lung Inflammation Increases Systemic Levels of PAI-1 and Activates Coagulation Through Distinct Mechanisms

BACKGROUND: Exposure of human populations to ambient particulate matter (PM) air pollution significantly contributes to the mortality attributable to ischemic cardiovascular events. We reported that mice treated with intratracheally instilled PM develop a prothrombotic state that requires the releas...

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Detalhes bibliográficos
Main Authors: Budinger, G. R. Scott, McKell, Joanne L., Urich, Daniela, Foiles, Nancy, Weiss, Ivy, Chiarella, Sergio E., Gonzalez, Angel, Soberanes, Saul, Ghio, Andrew J., Nigdelioglu, Recep, Mutlu, Ece A., Radigan, Kathryn A., Green, David, Kwaan, Hau C., Mutlu, Gökhan M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3073968/
https://ncbi.nlm.nih.gov/pubmed/21494547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0018525
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