Normal tissue radioprotection by amifostine via Warburg-type effects

The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of amifostine on human basal metabolism, mouse liver metabolism and on normal and tumor hepatic cells were studied. Indirect calorimetric canopy tests showed significant reductions in oxygen consumption...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Koukourakis, Michael I., Giatromanolaki, Alexandra, Zois, Christos E., Kalamida, Dimitra, Pouliliou, Stamatia, Karagounis, Ilias V., Yeh, Tzu-Lan, Abboud, Martine I., Claridge, Timothy D. W., Schofield, Christopher J., Sivridis, Efthimios, Simopoulos, Costantinos, Tokmakidis, Savvas P., Harris, Adrian L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978965/
https://ncbi.nlm.nih.gov/pubmed/27507219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30986
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