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Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria

Endothelial nitric oxide synthase (eNOS) deficiency exacerbates proteinuria and renal injury in several glomerular diseases, but the underlying mechanism is not fully understood. We recently showed that heparanase is essential for the development of experimental diabetic nephropathy and glomerulonep...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Garsen, Marjolein, Rops, Angelique L., Li, Jinhua, van Beneden, Katrien, van den Branden, Christiane, Berden, Jo HM, Rabelink, Ton J., van der Vlag, Johan
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978400/
https://ncbi.nlm.nih.gov/pubmed/27505185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160894
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