Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria

Endothelial nitric oxide synthase (eNOS) deficiency exacerbates proteinuria and renal injury in several glomerular diseases, but the underlying mechanism is not fully understood. We recently showed that heparanase is essential for the development of experimental diabetic nephropathy and glomerulonep...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garsen, Marjolein, Rops, Angelique L., Li, Jinhua, van Beneden, Katrien, van den Branden, Christiane, Berden, Jo HM, Rabelink, Ton J., van der Vlag, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978400/
https://ncbi.nlm.nih.gov/pubmed/27505185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160894
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