Endothelial Nitric Oxide Synthase Prevents Heparanase Induction and the Development of Proteinuria

Endothelial nitric oxide synthase (eNOS) deficiency exacerbates proteinuria and renal injury in several glomerular diseases, but the underlying mechanism is not fully understood. We recently showed that heparanase is essential for the development of experimental diabetic nephropathy and glomerulonep...

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Publicat a:PLoS One
Autors principals: Garsen, Marjolein, Rops, Angelique L., Li, Jinhua, van Beneden, Katrien, van den Branden, Christiane, Berden, Jo HM, Rabelink, Ton J., van der Vlag, Johan
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978400/
https://ncbi.nlm.nih.gov/pubmed/27505185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160894
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