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Conformational selectivity in cytochrome P450 redox partner interactions
The heme iron of cytochromes P450 must be reduced to bind and activate molecular oxygen for substrate oxidation. Reducing equivalents are derived from a redox partner, which requires the formation of a protein–protein complex. A subject of increasing discussion is the role that redox partner binding...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2016
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4978276/ https://ncbi.nlm.nih.gov/pubmed/27439869 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606474113 |
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