Severity and Frequency of Proximal Tubule Injury Determines Renal Prognosis

AKI increases the risk of developing CKD, but the mechanisms linking AKI to CKD remain unclear. Because proximal tubule injury is the mainstay of AKI, we postulated that proximal tubule injury triggers features of CKD. We generated a novel mouse model to induce proximal tubule–specific adjustable in...

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Bibliografiset tiedot
Julkaisussa:J Am Soc Nephrol
Päätekijät: Takaori, Koji, Nakamura, Jin, Yamamoto, Shinya, Nakata, Hirosuke, Sato, Yuki, Takase, Masayuki, Nameta, Masaaki, Yamamoto, Tadashi, Economides, Aris N., Kohno, Kenji, Haga, Hironori, Sharma, Kumar, Yanagita, Motoko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Nephrology 2016
Aiheet:
Basic Research
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4978049/
https://ncbi.nlm.nih.gov/pubmed/26701981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015060647
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