Obesity-induced kidney injury is attenuated by amelioration of aberrant PHD2 activation in proximal tubules

The involvement of tissue ischemia in obesity-induced kidney injury remains to be elucidated. Compared with low fat diet (LFD)-mice, high fat diet (HFD)-fed mice became obese with tubular enlargement, glomerulomegaly and peritubular capillary rarefaction, and exhibited both tubular and glomerular da...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Futatsugi, Koji, Tokuyama, Hirobumi, Shibata, Shinsuke, Naitoh, Makiko, Kanda, Takeshi, Minakuchi, Hitoshi, Yamaguchi, Shintaro, Hayashi, Koichi, Minamishima, Yoji Andrew, Yanagita, Motoko, Wakino, Shu, Itoh, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5101521/
https://ncbi.nlm.nih.gov/pubmed/27827416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep36533
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