Ghrelin Protects against Renal Damages Induced by Angiotensin-II via an Antioxidative Stress Mechanism in Mice

We explored the renal protective effects by a gut peptide, Ghrelin. Daily peritoneal injection with Ghrelin ameliorated renal damages in continuously angiotensin II (AngII)-infused C57BL/6 mice as assessed by urinary excretion of protein and renal tubular markers. AngII-induced increase in reactive...

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Detalhes bibliográficos
Main Authors: Fujimura, Keiko, Wakino, Shu, Minakuchi, Hitoshi, Hasegawa, Kazuhiro, Hosoya, Koji, Komatsu, Motoaki, Kaneko, Yuka, Shinozuka, Keisuke, Washida, Naoki, Kanda, Takeshi, Tokuyama, Hirobumi, Hayashi, Koichi, Itoh, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3991592/
https://ncbi.nlm.nih.gov/pubmed/24747517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094373
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