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The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

Type I interferons (including IFNαβ) are innate cytokines that may contribute to pathogenesis during Mycobacterium tuberculosis (Mtb) infection. To induce IFNβ, Mtb must gain access to the host cytosol and trigger stimulator of interferon genes (STING) signaling. A recently proposed model suggests t...

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Vydáno v:PLoS Pathog
Hlavní autoři: Wiens, Kirsten E., Ernst, Joel D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976988/
https://ncbi.nlm.nih.gov/pubmed/27500737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005809
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