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Type I Interferon is Pathogenic During Chronic Mycobacterium africanum Infection

Type I interferons (IFNs, including IFN-αβ) contribute to the pathogenesis of Mycobacterium tuberculosis strains that induce high IFN-αβ levels. In the current study we examined the role of IFN-αβ during infection with a Mycobacterium africanum strain that induces low IFN-β levels. We infected wild-...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Wiens, Kirsten E., Ernst, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5142099/
https://ncbi.nlm.nih.gov/pubmed/27803172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw519
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