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The Mechanism for Type I Interferon Induction by Mycobacterium tuberculosis is Bacterial Strain-Dependent

Type I interferons (including IFNαβ) are innate cytokines that may contribute to pathogenesis during Mycobacterium tuberculosis (Mtb) infection. To induce IFNβ, Mtb must gain access to the host cytosol and trigger stimulator of interferon genes (STING) signaling. A recently proposed model suggests t...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Wiens, Kirsten E., Ernst, Joel D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976988/
https://ncbi.nlm.nih.gov/pubmed/27500737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005809
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