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Type I interferon signaling is required for activation of the inflammasome during Francisella infection

Francisella tularensis is a pathogenic bacterium whose virulence is linked to its ability to replicate within the host cell cytosol. Entry into the macrophage cytosol activates a host-protective multimolecular complex called the inflammasome to release the proinflammatory cytokines interleukin (IL)-...

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Detalhes bibliográficos
Main Authors: Henry, Thomas, Brotcke, Anna, Weiss, David S., Thompson, Lucinda J., Monack, Denise M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118578/
https://ncbi.nlm.nih.gov/pubmed/17452523
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062665
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