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In vivo negative selection screen identifies genes required for Francisella virulence
Francisella tularensis subverts the immune system to rapidly grow within mammalian hosts, often causing tularemia, a fatal disease. This pathogen targets the cytosol of macrophages where it replicates by using the genes encoded in the Francisella pathogenicity island. However, the bacteria are recog...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1832217/ https://ncbi.nlm.nih.gov/pubmed/17389372 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0609675104 |
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