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Type I interferon signaling is required for activation of the inflammasome during Francisella infection
Francisella tularensis is a pathogenic bacterium whose virulence is linked to its ability to replicate within the host cell cytosol. Entry into the macrophage cytosol activates a host-protective multimolecular complex called the inflammasome to release the proinflammatory cytokines interleukin (IL)-...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118578/ https://ncbi.nlm.nih.gov/pubmed/17452523 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20062665 |
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