Efficacy of Tumor-Targeting Salmonella A1-R on a Melanoma Patient-Derived Orthotopic Xenograft (PDOX) Nude-Mouse Model

Tumor-targeting Salmonella enterica serovar Typhimurium A1-R (Salmonella A1-R) had strong efficacy on a melanoma patient-derived orthotopic xenograft (PDOX) nude-mouse model. GFP-expressing Salmonella A1-R highly and selectively colonized the PDOX melanoma and significantly suppressed tumor growth (...

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Udgivet i:PLoS One
Main Authors: Yamamoto, Mako, Zhao, Ming, Hiroshima, Yukihiko, Zhang, Yong, Shurell, Elizabeth, Eilber, Fritz C., Bouvet, Michael, Noda, Makoto, Hoffman, Robert M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976963/
https://ncbi.nlm.nih.gov/pubmed/27500926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160882
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