Efficacy of Tumor-Targeting Salmonella typhimurium A1-R against Malignancies in Patient-Derived Orthotopic Xenograft (PDOX) Murine Models

We developed tumor-targeting Salmonella typhimurium (S. typhimurium) A1-R, a facultative anaerobe that is an auxotroph of leucine and arginine. The tumor-targeting efficacy of S. typhimurium A1-R was demonstrated in vivo and vitro using several malignant cell lines including melanoma, sarcoma, gliom...

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Detalhes bibliográficos
Publicado no:Cells
Main Authors: Murakami, Takashi, Hiroshima, Yukihiko, Miyake, Kentaro, Kiyuna, Tasuku, Endo, Itaru, Zhao, Ming, Hoffman, Robert M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6628209/
https://ncbi.nlm.nih.gov/pubmed/31208120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells8060599
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