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ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia with no cure at present. Cholesterol metabolism is closely associated with AD at several stages. ACAT1 converts free cholesterol to cholesteryl esters, and plays important roles in cellular cholesterol homeostasis. Recent studies sho...

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Bibliografske podrobnosti
izdano v:Future Med Chem
Main Authors: Shibuya, Yohei, Chang, Catherine CY, Chang, Ta-Yuan
Format: Artigo
Jezik:Inglês
Izdano: Future Science Ltd 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976859/
https://ncbi.nlm.nih.gov/pubmed/26669800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.161
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