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ACAT1/SOAT1 as a therapeutic target for Alzheimer's disease

Alzheimer's disease (AD) is the most common cause of dementia with no cure at present. Cholesterol metabolism is closely associated with AD at several stages. ACAT1 converts free cholesterol to cholesteryl esters, and plays important roles in cellular cholesterol homeostasis. Recent studies sho...

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Detalhes bibliográficos
Publicado no:Future Med Chem
Main Authors: Shibuya, Yohei, Chang, Catherine CY, Chang, Ta-Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: Future Science Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976859/
https://ncbi.nlm.nih.gov/pubmed/26669800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.15.161
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