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Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice
Hantavirus infections cause severe emerging diseases in humans and are associated with high mortality rates; therefore, they have become a global public health concern. Our previous study showed that the CD8(+) T-cell epitope aa129–aa137 (FVVPILLKA, FA9) of the Hantaan virus (HTNV) nucleoprotein (NP...
Shranjeno v:
izdano v: | Front Immunol |
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Main Authors: | , , , , , , , , , , , |
Format: | Artigo |
Jezik: | Inglês |
Izdano: |
Frontiers Media S.A.
2016
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4976285/ https://ncbi.nlm.nih.gov/pubmed/27551282 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00298 |
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