Structure and Function of HLA-A*02-Restricted Hantaan Virus Cytotoxic T-Cell Epitope That Mediates Effective Protective Responses in HLA-A2.1/K(b) Transgenic Mice

Hantavirus infections cause severe emerging diseases in humans and are associated with high mortality rates; therefore, they have become a global public health concern. Our previous study showed that the CD8(+) T-cell epitope aa129–aa137 (FVVPILLKA, FA9) of the Hantaan virus (HTNV) nucleoprotein (NP...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ma, Ying, Cheng, Linfeng, Yuan, Bin, Zhang, Yusi, Zhang, Chunmei, Zhang, Yun, Tang, Kang, Zhuang, Ran, Chen, Lihua, Yang, Kun, Zhang, Fanglin, Jin, Boquan
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2016
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976285/
https://ncbi.nlm.nih.gov/pubmed/27551282
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2016.00298
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