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Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells

Coordinated polarization of epithelial cells is a key step during morphogenesis that leads to the formation of an apical lumen. Rab11 and its interacting protein FIP5 are necessary for the targeting of apical endosomes to the midbody and apical membrane initiation site (AMIS) during lumenogenesis. H...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Mangan, Anthony J., Sietsema, Daniel V., Li, Dongying, Moore, Jeffrey K., Citi, Sandra, Prekeris, Rytis
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976216/
https://ncbi.nlm.nih.gov/pubmed/27484926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12426
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