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Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells

Coordinated polarization of epithelial cells is a key step during morphogenesis that leads to the formation of an apical lumen. Rab11 and its interacting protein FIP5 are necessary for the targeting of apical endosomes to the midbody and apical membrane initiation site (AMIS) during lumenogenesis. H...

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Publicat a:Nat Commun
Autors principals: Mangan, Anthony J., Sietsema, Daniel V., Li, Dongying, Moore, Jeffrey K., Citi, Sandra, Prekeris, Rytis
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976216/
https://ncbi.nlm.nih.gov/pubmed/27484926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12426
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