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Cingulin and actin mediate midbody-dependent apical lumen formation during polarization of epithelial cells

Coordinated polarization of epithelial cells is a key step during morphogenesis that leads to the formation of an apical lumen. Rab11 and its interacting protein FIP5 are necessary for the targeting of apical endosomes to the midbody and apical membrane initiation site (AMIS) during lumenogenesis. H...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Mangan, Anthony J., Sietsema, Daniel V., Li, Dongying, Moore, Jeffrey K., Citi, Sandra, Prekeris, Rytis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976216/
https://ncbi.nlm.nih.gov/pubmed/27484926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12426
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