Effect of anti-IL-15 administration on T cell and NK cell homeostasis in rhesus macaques

IL-15 has been implicated as a key regulator of T and NK cell homeostasis in multiple systems; however, its specific role in maintaining peripheral T and NK cell populations relative to other gamma-chain (γc) cytokines has not been fully defined in primates. Here, we address this question by determi...

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Vydáno v:J Immunol
Hlavní autoři: DeGottardi, Maren Q., Okoye, Afam A., Vaidya, Mukta, Talla, Aarthi, Konfe, Audrie L., Reyes, Matthew D., Clock, Joseph A., Duell, Derick M., Legasse, Alfred W., Sabnis, Amit, Park, Byung S., Axthelm, Michael K., Estes, Jacob D., Reinmann, Keith A., Sekaly, Rafick-Pierre, Picker, Louis J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4976006/
https://ncbi.nlm.nih.gov/pubmed/27430715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600065
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