Resistance Analyses of HCV NS3/4A Protease and NS5B Polymerase from Clinical Studies of Deleobuvir and Faldaprevir

BACKGROUND & AIM: The resistance profile of anti-hepatitis C virus (HCV) agents used in combination is important to guide optimal treatment regimens. We evaluated baseline and treatment-emergent NS3/4A and NS5B amino-acid variants among HCV genotype (GT)-1a and -1b-infected patients treated with...

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Publicat a:PLoS One
Autors principals: Berger, Kristi L., Sarrazin, Christoph, Nelson, David R., Scherer, Joseph, Sha, Nanshi, Marquis, Martin, Côté-Martin, Alexandra, Vinisko, Richard, Stern, Jerry O., Mensa, Federico J., Kukolj, George
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4975400/
https://ncbi.nlm.nih.gov/pubmed/27494410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160668
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