Baseline Hepatitis C Virus (HCV) NS3 Polymorphisms and Their Impact on Treatment Response in Clinical Studies of the HCV NS3 Protease Inhibitor Faldaprevir

A challenge to the treatment of chronic hepatitis C with direct-acting antivirals is the emergence of drug-resistant hepatitis C virus (HCV) variants. HCV with preexisting polymorphisms that are associated with resistance to NS3/4A protease inhibitors have been detected in patients with chronic hepa...

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Bibliographic Details
Main Authors: Berger, Kristi L., Triki, Ibtissem, Cartier, Mireille, Marquis, Martin, Massariol, Marie-Josée, Böcher, Wulf O., Datsenko, Yakov, Steinmann, Gerhard, Scherer, Joseph, Stern, Jerry O., Kukolj, George
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3910880/
https://ncbi.nlm.nih.gov/pubmed/24217701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01976-13
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