Baseline Polymorphisms and Emergence of Drug Resistance in the NS3/4A Protease of Hepatitis C Virus Genotype 1 following Treatment with Faldaprevir and Pegylated Interferon Alpha 2a/Ribavirin in Phase 2 and Phase 3 Studies

Analysis of data pooled from multiple phase 2 (SILEN-C1 to 3) and phase 3 studies (STARTVerso1 to 4) of the hepatitis C virus (HCV) nonstructural protein 3/4A (NS3/4A) protease inhibitor faldaprevir plus pegylated interferon alpha/ribavirin (PR) provides a comprehensive evaluation of baseline and tr...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Berger, K. L., Scherer, J., Ranga, M., Sha, N., Stern, J. O., Quinson, A.-M., Kukolj, G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4576130/
https://ncbi.nlm.nih.gov/pubmed/26195509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00932-15
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