ITPA Genotypes Predict Anemia but Do Not Affect Virological Response with Interferon-Free Faldaprevir, Deleobuvir, and Ribavirin for HCV Infection

BACKGROUND & AIM: Whether inosine triphosphatase (ITPA) gene polymorphisms predict anemia during interferon-free therapy in chronic hepatitis C virus (HCV)-infected patients is unknown. We examined the relationship between two ITPA polymorphisms, anemia, and sustained virological response 12 wee...

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Publicat a:PLoS One
Autors principals: Asselah, Tarik, Zeuzem, Stefan, Soriano, Vicente, Bronowicki, Jean-Pierre, Lohse, Ansgar W., Müllhaupt, Beat, Schuchmann, Marcus, Bourlière, Marc, Buti, Maria, Roberts, Stuart K., Gane, Edward J., Stern, Jerry O., Voss, Florian, Baum, Patrick, Gallivan, John-Paul, Böcher, Wulf O., Mensa, Federico J.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4674133/
https://ncbi.nlm.nih.gov/pubmed/26650626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0144004
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