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Extremely long range chromatin loops link topological domains to facilitate a diverse antibody repertoire
Early B cell development is characterized by large scale Igh locus contraction prior to V(D)J recombination to facilitate a highly diverse Ig repertoire. However, an understanding of the molecular architecture that mediates locus contraction remains unclear. We have combined high resolution chromoso...
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| 發表在: | Cell Rep |
|---|---|
| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2016
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4975037/ https://ncbi.nlm.nih.gov/pubmed/26804913 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.083 |
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