Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.

Transgenic mice were produced containing the adipocyte-specific regulatory region from the adipocyte P2 (aP2) gene linked to the simian virus 40 transforming genes. Most of the transgenic mice developed brown fat tumors (hibernomas) in their interscapular brown adipose tissue. Hibernoma formation wa...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Ross, S R, Choy, L, Graves, R A, Fox, N, Solevjeva, V, Klaus, S, Ricquier, D, Spiegelman, B M
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7561
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