Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.

We investigated the relative activity at which fully occupied human beta 1- and beta 2-adrenergic receptors (beta 1AR and beta 2AR) activate the stimulatory G protein (Gs)/adenylyl cyclase (AC) system in isolated membranes. The receptors were cloned and coexpressed in permanent cell lines at beta 1/...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Levy, F O, Zhu, X, Kaumann, A J, Birnbaumer, L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10798
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