Efficacy of beta 1-adrenergic receptors is lower than that of beta 2-adrenergic receptors.
We investigated the relative activity at which fully occupied human beta 1- and beta 2-adrenergic receptors (beta 1AR and beta 2AR) activate the stimulatory G protein (Gs)/adenylyl cyclase (AC) system in isolated membranes. The receptors were cloned and coexpressed in permanent cell lines at beta 1/...
Tallennettuna:
| Julkaisussa: | Proc Natl Acad Sci U S A |
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| Päätekijät: | , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
National Academy of Sciences
1993
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47865/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8248173/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.22.10798 |
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