Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.

Transgenic mice were produced containing the adipocyte-specific regulatory region from the adipocyte P2 (aP2) gene linked to the simian virus 40 transforming genes. Most of the transgenic mice developed brown fat tumors (hibernomas) in their interscapular brown adipose tissue. Hibernoma formation wa...

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Detalhes bibliográficos
Main Authors: Ross, S R, Choy, L, Graves, R A, Fox, N, Solevjeva, V, Klaus, S, Ricquier, D, Spiegelman, B M
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC49750/
https://ncbi.nlm.nih.gov/pubmed/1323843
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