Hibernoma formation in transgenic mice and isolation of a brown adipocyte cell line expressing the uncoupling protein gene.

Transgenic mice were produced containing the adipocyte-specific regulatory region from the adipocyte P2 (aP2) gene linked to the simian virus 40 transforming genes. Most of the transgenic mice developed brown fat tumors (hibernomas) in their interscapular brown adipose tissue. Hibernoma formation wa...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ross, S R, Choy, L, Graves, R A, Fox, N, Solevjeva, V, Klaus, S, Ricquier, D, Spiegelman, B M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1992
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49750/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1323843/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.16.7561
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