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Optimal Synthetic Glycosylation of a Therapeutic Antibody
Glycosylation patterns in antibodies critically determine biological and physical properties but their precise control is a significant challenge in biology and biotechnology. We describe herein the optimization of an endoglycosidase‐catalyzed glycosylation of the best‐selling biotherapeutic Hercept...
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| Publicado en: | Angew Chem Weinheim Bergstr Ger |
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| Autores principales: | , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
John Wiley and Sons Inc.
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974915/ https://ncbi.nlm.nih.gov/pubmed/27546920 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ange.201508723 |
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