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Stress-dependent phosphorylation of myocardin-related transcription factor A (MRTF-A) by the p38(MAPK)/MK2 axis

Myocardin-related transcription factor A (MRTF-A) is a known actin-regulated transcriptional coactivator of serum response factor (SRF). Stimulation of actin polymerization activates MRTF-A by releasing it from G-actin and thus allowing it to bind to and activate SRF. Here, we compared protein phosp...

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Publicat a:Sci Rep
Autors principals: Ronkina, Natalia, Lafera, Juri, Kotlyarov, Alexey, Gaestel, Matthias
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974569/
https://ncbi.nlm.nih.gov/pubmed/27492266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31219
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