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Phosphorylation of steroid receptor coactivator-3 (SRC-3) at serine 857 is regulated by the p38(MAPK)-MK2 axis and affects NF-κB-mediated transcription

Steroid receptor coactivator-3 (SRC-3) regulates the activity of both nuclear hormone receptors and a number of key transcription factors. It is implicated in the regulation of cell proliferation, inflammation and in the progression of several common cancers including breast, colorectal and lung tum...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Shrestha, Anup, Bruckmueller, Henrike, Kildalsen, Hanne, Kaur, Gurjit, Gaestel, Matthias, Wetting, Hilde Ljones, Mikkola, Ingvild, Seternes, Ole-Morten
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7347898/
https://ncbi.nlm.nih.gov/pubmed/32647362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68219-4
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