טוען...
A single-molecule view of transcription reveals convoys of RNA polymerases and multi-scale bursting
Live-cell imaging has revealed unexpected features of gene expression. Here using improved single-molecule RNA microscopy, we show that synthesis of HIV-1 RNA is achieved by groups of closely spaced polymerases, termed convoys, as opposed to single isolated enzymes. Convoys arise by a Mediator-depen...
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| הוצא לאור ב: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2016
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4974459/ https://ncbi.nlm.nih.gov/pubmed/27461529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12248 |
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