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3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yadav, Vivek R., Prasad, Sahdeo, Gupta, Subash C., Sung, Bokyung, Phatak, Sharangdhar S., Zhang, Shuxing, Aggarwal, Bharat B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974409/
https://ncbi.nlm.nih.gov/pubmed/27496967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.A111.274613
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