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Modification of Cysteine Residue in p65 Subunit of Nuclear Factor-κB by Picroliv Suppresses NF-κB-Regulated Gene Products and Potentiates Apoptosis

Picroliv, an iridoid glycoside derived from the plant Picrorhiza kurroa, is used traditionally to treat fever, asthma, hepatitis and other inflammatory conditions. However, the exact mechanism of its therapeutic action is still unknown. Because NF-κB activation plays a major role in inflammation and...

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Hlavní autoři: Anand, Preetha, Kunnumakkara, Ajaikumar B., Harikumar, Kuzhuvelil B., Ahn, Kwang S., Badmaev, Vladimir, Aggarwal, Bharat B.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2673720/
https://ncbi.nlm.nih.gov/pubmed/18974130
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-1902
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