How Glycosaminoglycans Promote Fibrillation of Salmon Calcitonin

Glycosaminoglycans (GAGs) bind all known amyloid plaques and help store protein hormones in (acidic) granular vesicles, but the molecular mechanisms underlying these important effects are unclear. Here we investigate GAG interactions with the peptide hormone salmon calcitonin (sCT). GAGs induce fast...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Malmos, Kirsten Gade, Bjerring, Morten, Jessen, Christian Moestrup, Nielsen, Erik Holm Toustrup, Poulsen, Ebbe T., Christiansen, Gunna, Vosegaard, Thomas, Skrydstrup, Troels, Enghild, Jan J., Pedersen, Jan Skov, Otzen, Daniel E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Protein Structure and Folding
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4974396/
https://ncbi.nlm.nih.gov/pubmed/27281819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.715466
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares