Prolonged Calcitonin Receptor Signaling by Salmon, but Not Human Calcitonin, Reveals Ligand Bias

Salmon calcitonin (sCT) and human calcitonin (hCT) are pharmacologically distinct. However, the reason for the differences is unclear. Here we analyze the differences between sCT and hCT on the human calcitonin receptor (CT((a))R) with respect to activation of cAMP signaling, β-arrestin recruitment,...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Andreassen, Kim Vietz, Hjuler, Sara Toftegaard, Furness, Sebastian G., Sexton, Patrick M., Christopoulos, Arthur, Nosjean, Olivier, Karsdal, Morten Asser, Henriksen, Kim
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3958426/
https://ncbi.nlm.nih.gov/pubmed/24643196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0092042
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker