A novel dual amylin and calcitonin receptor agonist, KBP‐089, induces weight loss through a reduction in fat, but not lean mass, while improving food preference

BACKGROUND AND PURPOSE: Obesity and associated co‐morbidities, such as type 2 diabetes and non‐alcoholic fatty liver disease, are major health challenges. Hence, there is an important need to develop weight loss therapies with the ability to reduce the co‐morbidities. EXPERIMENTAL APPROACH: The effe...

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Vydáno v:Br J Pharmacol
Hlavní autoři: Gydesen, Sofie, Hjuler, Sara Toftegaard, Freving, Zenia, Andreassen, Kim Vietz, Sonne, Nina, Hellgren, Lars I, Karsdal, Morten Asser, Henriksen, Kim
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2017
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345549/
https://ncbi.nlm.nih.gov/pubmed/28109166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13723
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